I would cut out holes for the lights.
Because plexi - glass , glass and even fine mesh screan filter out the UV Rays .I would cut out holes for the lights.
I would make it waterproof, then you could use damp coco bark, or a slightly damp medium.Not to many use foggers, If your table is water proof you would wet the substrate to increase the humidity.
Under my enclosures I dig dry wells that gives the water someplace to goI was just curious as to if anyone had suggestions or recommendations for things they did to help offer protection... we get hit pretty hard where we are so I thought I'd ask if anyone had recommendations or suggestions. We have a neighbor who lost a sulcata in a storm last year (seems he wasn't smart enough to get out of the way and ended up hanging out in a low spot..) so I'm wanting to do what I can to offer as much safety and protection as I can.